Treatment-Resistant Depression

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Treatment-resistant depression is the state when a person’s organism does not respond to the antidepressant therapy. There are two conditions distinguished here: partial responders and nonresponders. About 10 and 30 % of people suffering depression and taking antidepressants need treatment-resistant depression therapy. Most commonly people who are treated with one drug type become partial or nonresponders and suffer treatment-resistant depression. Various factors can cause treatment-resistant depression. Misdiagnosed medical condition is only one of them. Therefore, a person experiencing treatment-resistant depression should be first reassessed to make sure the original diagnosis of depression was correct.

Another factor causing treatment-resistant depression is the incorrect prescription: too low doses and too short periods of time the medicine is taken can result in the treatment-resistant depression and furthermore cause addiction to the drug. Besides, improper nutrition can also contribute to the treatment-resistant depression. So what are the possible ways out? As we have already mentioned, in case of treatment-resistant depression the patient should first be reassessed. The next step is generally maximizing the dosage or duration of therapy. One possible method of eliminating treatment-resistant depression is to switch to another antidepressant with a different mechanism of action.

However this method is inadequately supported by recorded data. Also dealing with treatment-resistant depression the doctor may choose to add a second antidepressant agent to the therapy. The extreme measure is electric shock treatment for depression used when dealing with severe depression treatment. However this method is not widely used today as it can result in serious complications and it is often avoided when dealing with treatment-resistant depression.

The conclusion here is that drug treatment for depression should be regarded as the most extreme method. As you can see it can result in treatment-resistant depression and addiction. Nowadays alternative treatments for depression are more preferable. Keep in mind that any subject can change over time, so be sure you keep up with the latest news about treatment-resistant depression.